Linguagem Oral, Poesia e Trissomia 21

A poesia, enquanto Arte, é um conceito ligado à cognição e emoção (Ricoeur, 1975). Segundo a teoria cognitivista, proporciona, também, conhecimento. A poesia espelha o pensamento realizado na palavra oral e escrita. A aplicação destes conceitos surge da ideia de que a palavra na poesia pode produzir emoções e sensações nas pessoas a quem ela é transmitida. A poesia tem funções multissensoriais que definem o input linguístico, desenvolvendo a linguagem ao nível das diferentes competências linguísticas. Existem vários estudos que envolvem pessoas com Trissomia 21, centrados na aprendizagem da leitura, escrita e seus domínios linguísticos. No entanto, é escassa a apresentação de casos que demonstrem a influência da poesia no desenvolvimento da linguagem oral, especialmente o seu uso nas práticas pedagógicas para o desenvolvimento linguístico-cognitivo em pessoas portadoras desse Síndrome. Este estudo pretende mostrar a importância do uso da poesia no desenvolvimento da linguagem oral de uma aluna com Trissomia 21, tendo como base um projeto de investigação-ação. A partir da identificação do caso-problema, a intervenção pedagógica procurou melhorar as competências linguísticas da aluna através do uso da poesia. Os resultados mostram evolução em todos os parâmetros linguísticos considerados. Estes dados levam-nos a crer que a utilização da poesia pode, também, constituir uma forma de promover a socialização e a autonomia, revelando os efeitos colaterais que podem decorrer deste tipo de intervenção

Para a unificação dos valores do perfeito e do mais-que-perfeito em português

Livro de homenagem à professora Maria Emília Ricardo Marque

MLFatigueDetection Machine Learning Based Walking Fatigue Detection

Leg fatigue can influence the gait patterns, therefore declining the postural stability and the motor performance, increasing the risk of falls. In order to improve the earlier detection of risks and the application of fall prevention strategies, automated solutions based on gait analysis must be developed. A sector of the population at risk is the workforce where a majority of workers admits to be fatigued and where falls can lead to serious workplace injuries or even deaths. In these cases, having the ability to detect if the user is fatigued in real time by simply using the motion sensors on the smartphone and processing it with machine learning can lead to the prevention of falls and the consequences these bring. Phones andwearable devices were studied for their ability to be used to extract inertial sensor’s data to provide enough information for the fatigue detection. Supervised machine learning algorithms, such as Support Vector Machines (SVM) and Neural Networks, will be used to process this information for fatigue level classification. Their performance will then be compared to find the best algorithm for fatigue detection. In addition to this comparative work, different conditions for the data collection and processing were tested in an effort to discover the optimal conditions for the implementation of the algorithms

Simplified model for the non-linear behaviour representation of reinforced concrete columns under biaxial bending

In the present paper a simplified model is proposed for the force-deformation behaviour of reinforced concrete members under biaxial loading combined with axial force. The starting point for the model development was an existing fixed-length plastic hinge element model that accounts for the non-linear hysteretic behaviour at the element end-sections, characterized by trilinear moment-curvature laws. To take into account the section biaxial behaviour, the existing model was adopted for both orthogonal lateral directions and an interaction function was introduced to couple the hysteretic response of both directions. To calibrate the interaction function it were used numerical results, obtained from fibre models, and experimental results. For the parameters identification, non-linear optimization approaches were adopted, namely: the gradient based methods followed by the genetic, evolutionary and nature-inspired algorithms. Finally, the simplified non-linear model proposed is validated through the analytical simulation of biaxial test results carried out in full-scale reinforced concrete columns

Equity valuation of Adidas AG

The purpose of this dissertation is to determine Adidas AG target share price as of 13th March of 2019 (day when the full 2018 annual report was published) by accomplishment of a more profound valuation of the Group. Consequently, issue an adequate investment recommendation of either buy, hold or sell by comparing it with the market price on that date. Therefore, the research question underlying this dissertation is: “What is the fair value of one common share at 13th March of 2019 and how different it is from the market price?” Adidas AG is the second largest representative of the global footwear and apparel market. The Company has strongly solidified its position over the past 4 years, surpassing its biggest competitor Nike, Inc. The valuation is determining upon a thorough analysis on the Sportswear Industry, followed by its current macroeconomics context and expected market trends, as well as a detailed company analysis in order to form accrued assumptions for the future. The primary method used was the Discounted cash-flow analysis as the major source for the aim of this dissertation, and secondly the forward-looking multiples valuation as a complementary approach. Both valuation methods reach a range price per share of €248,4-€281,3 which implies a BUY recommendation with an upside of 21%-37%. Subsequently, my valuation is compared with equity report issued by Warburg Research and Piper Jaffray & Co. The main differences between the valuation methodologies and assumptions are analysed.O objetivo desta dissertação é determinar o preço por ação da Adidas AG a partir de 13 de março de 2019 (dia em que o relatório e contas completo de 2018 foi publicado) realizando uma avaliação aprofundada do grupo. Consequentemente, uma recomendação de investimento adequada é emitida (comprar, segurar ou vender) comparativamente com o preço de mercado nessa data. Portanto, "Qual é o valor justo de uma ação a 13 de março de 2019 e como difere do preço de mercado?" é efetivamente a questão subjacente. Adidas AG é a segunda maior representante do mercado mundial de calçados e vestuário. A empresa tem solidificado fortemente a sua posição ao longo dos últimos 4 anos, superando o seu maior concorrente Nike, Inc. A avaliação é determinada através de uma análise minuciosa da indústria desportiva, seguida pelo seu contexto macroeconómico atual e pelas tendências esperadas do mercado, assim como uma análise detalhada da Empresa, de forma a tingir suposições corretas para o futuro. O método primário utilizado foi a análise de fluxo de caixa descontado como a principal fonte para o objetivo desta dissertação e, em segundo lugar, a avaliação por múltiplos como uma abordagem complementar. Ambos os métodos de avaliação atingem um preço de variação por ação de € 248,4-€ 281,3 o que implica uma recomendação de COMPRA que se traduz numa valorização de 21%-37%. Subsequentemente, a avaliação é comparada com o relatório emitido por Warburg Research e por Piper Jaffray & Co

The Alkaloid Alstonine: A Review of Its Pharmacological Properties

Indole compounds, related to the metabolism of tryptophan, constitute an extensive family, and are found in bacteria, plants and animals. Indolic compounds possess significant and complex physiological roles, and especially indole alkaloids have historically constituted a class of major importance in the development of new plant derived drugs. The indole alkaloid alstonine has been identified as the major component of a plant-based remedy, used in Nigeria to treat mental illnesses by traditional psychiatrists. Although it is certainly difficult to compare the very concept of mental disorders in different cultures, the traditional use of alstonine is remarkably compatible with its profile in experimental animals. Even though alstonine in mice models shows a psychopharmacological profile closer to the newer atypical antipsychotic agents, it also shows important differences and what seems to be an exclusive mechanism of action, not entirely clarified at this point. Considering the seemingly unique mode of action of alstonine and that its traditional use can be viewed as indicative of bioavailability and safety, this review focuses on the effects of alstonine in the central nervous system, particularly on its unique profile as an antipsychotic agent. We suggest that a thorough understanding of traditional medical concepts of health and disease in general and traditional medical practices in particular, can lead to true innovation in paradigms of drug action and development. Overall, the study of this unique indole alkaloid may be considered as another example of the richness of medicinal plants and traditional medical systems in the discovery of new prototypic drugs

Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery

Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC). Methods: This study included 69 eyes of 69 patient’s eyes with pterygium. Clinical data concerning patient demography, preoperative examination including pterygium morphology, recurrence clinical assessment, and complications after CLAU with (MMC+) and without (MMC-) intraoperative MMC were all registered at 1 month and 6 months after surgery. Results: Thirty-five eyes were included in MMC+ and 34 in MMC-. Preoperative data were similar in both groups (Student’s t test and Fisher’s exact test; p > 0.05). Thirty-four (49.6%) eyes in the whole sample showed at least one inflammatory complication at 1 month after surgery. MMC- group showed a significantly higher number of cases with complications (p 0.05; Chi2 test). Pyogenic granuloma developed at the surgical site in three eyes (4.37%), two of those granulomas were at the MMC- group (p > 0.05). Tendency for recurrences was significantly different between both groups (p = 0.0001; Fisher’s exact test) at the end of 6 months. Thirteen (38%) eyes showed recurrence in MMC- and no cases were displayed in MMC+. Presence of at least 1 inflammatory event was only seen in 16 (23%) cases, all of them in MMC-. Specifically, 15 (44%) eyes showed hyperemia and one (3%) eye presented conjunctival hemorrhages. No new cases of pyogenic granuloma or graft contraction were seen at this time point in both groups. Hyperemia was the only specific event with significant differences between MMC- and MMC+ (p = 0.0001; Fisher’s exact test) at 6 months after surgery. Conclusion: The eyes receiving intraoperative MMC after CLAU seem to present less hyperemia and graft contraction after surgery than those that did not receive MMC as an adjuvant factor. Intraoperative MMC could be associated with a lower recurrence rates.Postprint (author's final draft